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課程名稱 |
結構生物學概論
Introduction to Structural Biology |
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開課學期 |
112-1 |
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授課對象 |
生化科技學系 |
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授課教師 |
楊啟伸 |
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課號 |
BST5008 |
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課程識別碼 |
B22EU0180 |
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班次 |
01 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期四6,7(13:20~15:10) |
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上課地點 |
農化二B10-1 |
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備註 |
本課程以英語授課。先修科目：生物化學上（或第一學期）或生物化學概論。
總人數上限：80人 |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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課程概述 |
This is a class integrates the concepts of structural biology and
bioinformatics. There are four major parts: 1) The basic principles
of how 20 amino acids affect protein structures. 2) The modern
methods currently adopted to resolve atomic resolution of protein
structures will be explained. 3) Software tools for protein structure
display and analysis, mainly using UCSF ChimeraX, will be
demonstrated. Several bioinformatics concepts and web servers will
be mentioned in this class. 4) The mechanism behind protein
structure and functional exertion will be emphasized and exercised
via student presentations. |
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課程目標 |
1. Understand amino acids and protein structures 2. Modern
approaches to resolve protein structure 3. Protein structure and
function 4. Resolve a protein structure by yourself (in the class) 5.
Software-based analysis of protein sequence 6. Create a video
showing protein in action 7. Current developments of protein
structural-related bioinformatics methods. 8. Do a structure-based
presentation。 |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
另約時間 備註： Make arrangement via E-mail. |
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指定閱讀 |
1. David Whitford (2005). Proteins : Structure and Function. John
Wiley & Sons, Hoboken, NJ. USA. 2. Arthur M. Eesk (2016).
Introduction to Protein Sciuence, 3rd ed., Oxford University Press,
Oxford, United Kindom. 3. Materials are updated according to
selected most updated journal publications. |
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參考書目 |
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評量方式
(僅供參考) |
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